Introducing Savie: A biodegradable surfactant enabling chemo-and biocatalysis and related reactions in recyclable water. Kincaid, J. R., Wong, M. J., Akporji, N., Gallou, F., Fialho, D. M., and Lipshutz, B. H. J. Am. Chem. Soc. 2023, 145, 4266-4278. doi.org/10.1021/jacs.2c13444
A plausible prebiotic path to nucleosides: ribosides and related aldosides generated from ribulose, fructose, and similar abiotic precursors. Roche, T. P., Fialho, D. M., Menor‐Salván, C., Krishnamurthy, R., Schuster, G. B., and Hud, N. V. Chem. Eur. J. 2023, 29, e202203036. doi.org/10.1002/chem.202203036
Direct formation of amide/peptide bonds from carboxylic acids: no traditional coupling reagents, 1-pot, and green. Freiberg, K. M., Kavthe, R. D., Thomas, R. M., Fialho, D. M., Dee, P., Scurria, M., and Lipshutz, B. H. Chem. Sci. 2023, 14, 3462-3469. doi.org/10.1039/D3SC00198A
A shared prebiotic formation of neopterins and guanine nucleosides from pyrimidine bases. Menor‐Salván, C., Burcar, B.T., Bouza, M., Fialho, D.M., Fernández, F.M., and Hud, N.V. Chem. Eur. J. 2022, 28, e202200714. doi.org/10.1002/chem.202200714
Depsipeptide Nucleic Acids: Prebiotic Formation, Oligomerization, and Self-Assembly of a New Proto-Nucleic Acid Candidate. Fialho, D.M., Karunakaran, S.C., Greeson, K.W., Martínez, I., Schuster, G.B., Krishnamurthy, R., and Hud, N.V. J. Am. Chem. Soc. 2021, 143, 13525-13537. doi.org/10.1021/jacs.1c02287
Copper-Catalyzed Asymmetric Reductions of Aryl/Heteroaryl Ketones under Mild Aqueous Micellar Conditions. Fialho, D.M., Etemadi-Davan, E., Langner, O.C., Takale, B.S., Gadakh, A., Sambasivam, G., and Lipshutz, B.H. Org. Lett. 2021, 23, 3282-3286. doi.org/10.1021/acs.orglett.1c00746
Conversion of Unprotected Aldose Sugars to Polyhydroxyalkyl and C-Glycosyl Furans via Zirconium Catalysis. Ronaghi, N., Fialho, D.M., Jones, C.W., and France, S. J. Org. Chem. 2020, 85, 15337-15346. doi.org/10.1021/acs.joc.0c02176
Prebiotic origin of pre-RNA building blocks in a urea “warm little pond” scenario. Menor-Salván, C., Bouza, M., Fialho, D.M., Burcar, B.T., Fernández, F.M., and Hud, N.V. ChemBioChem. 2020, 21, 1-8. doi.org/10.1002/cbic.202000510
Glycosylation of a model proto-RNA nucleobase with non-ribose sugars: implications for the prebiotic synthesis of nucleosides. Fialho, D.M., Clarke, K.C., Moore, M.K., Schuster, G.B., Krishnamurthy, R., and Hud, N.V. Org. Biomol. Chem. 2016, 16, 1263-1271. doi.org/10.1039/C7OB03017G
Spontaneous formation and base pairing of plausible prebiotic nucleotides in water. Cafferty, B.J., Fialho, D.M., Khanam, J., Krishnamurthy, R., and Hud, N.V. Nat. Commun. 2016, 7, 1-8. doi.org/10.1038/ncomms11328
A Modular Platform for Covalent, Photoswitchable Control over Enzyme Activity. Trauner, D., and Fialho, D.M. Synfacts 2023, 19(08), 0831. doi.org.10.1055/s-0042-1751961
Synthesis of Urazolyl-Tyrosine Macrocyclic Peptides via Chemoselective Oxidative C–N Coupling. Trauner, D., and Fialho, D.M. Synfacts 2023, 19.07: 0728. doi.org/10.1055/s-0042-1751932
Alcohols as Substrates for Metallaphotoredox-Catalyzed C(sp3)–C(sp3) Cross-Coupling. Trauner, D., and Fialho, D.M. Synfacts 2023, 19.06: 0613. doi.org/10.1055/s-0042-1751889
Enantioselective Synthesis of Drug Precursors by Photo-HAT and Facially Selective Radical Capture. Trauner, D., and Fialho, D.M. Synfacts 2023, 19.05: 0514. doi.org/10.1055/s-0042-1752495
Bioorthogonal “Click-and-Release” of Iminosydnones to Give Water-Stable Isocyanates. Trauner, D., and Fialho, D.M. Synfacts 2023, 19.04: 0405. doi.org/10.1055/s-0042-1752411
Prebiotic syntheses of noncanonical nucleosides and nucleotides. Fialho, D.M., Roche, T.P., and Hud, N.V. Chem. Rev. 2020, 120, 4806-4830. doi.org/10.1021/acs.chemrev.0c00069
RNA nucleosides built in one prebiotic pot. Hud, N.V. and Fialho, D.M. Science 2019, 366, 32-33. doi.org/10.1126/science.aaz1130
Searching for Possible Ancestors of RNA: The Self-Assembly Hypothesis for the Origin of Proto-RNA. Cafferty, B.J., Fialho, D.M., and Hud, N.V. In Prebiotic Chemistry and Chemical Evolution of Nucleic Acids 2018, 143-174. Ed: Salván, C.M. Springer, Cham. doi.org/10.1007/978-3-319-93584-3_5